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Centre for Suicide Research | Research | Genetics |


Genetic aspects of suicidal behaviour


We have conducted a study of possible associations between DSH and genetic factors by investigating the distribution of polymorphisms of genes influencing brain transmitter systems within patient groups and between patients and community controls. This study was funded by the American Foundation for Suicide Prevention.



Pooley, E. C., Houston, K., Hawton, K., Harrison, P. J. (2003) Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes. Psychological Medicine, 33, 775-784.


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