In addition to primary research, there are a number of Centre activities in research synthesis and implementation. These activities are focused on understanding how primary research can be better translated into improved patient outcomes. Research syntheses, such as systematic reviews, help us better utilise and interpret existing research. Most of the reviews submitted by the Centre are published through the CCDAN - the Depression, Anxiety and Neurosis group - but is also involved in systematic reviews in a number of other areas.

Reviews:

• Fluoxetine versus other types of pharmacotherapy for depression
• Folate for depressive disorders
• Haloperidol alone or in combination for acute mania
• Incentives and disincentives to participation by clinicians in randomised controlled trials
• Inositol for depressive disorders
• Lithium for maintenance treatment of mood disorders
• Lithium versus antidepressants in the long-term treatment of unipolar affective disorder
• Olanzapine alone or in combination for acute mania
• Olanzapine in long-term treatment for bipolar disorder
• Oxcarbazepine in the maintenance treatment of bipolar disorder
• Pharmacological treatment for psychotic depression
• Risperidone alone or in combination for acute mania
• Risperidone in long-term treatment for bipolar disorder
• Selective serotonin reuptake inhibitors (SSRIs) versus other antidepressants for depression
• Tiagabine in the maintenance treatment of bipolar disorders
• Tiagabine in the treatment of acute affective episodes in bipolar disorder
• Treatment discontinuation with selective serotonin reuptake inhibitors (SSRIs) versus tricyclic antidepressants (TCAs)
• Valproate for acute mood episodes in bipolar disorder
• Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder

Protocols:

• Aripiprazole alone or in combination for acute mania
• Lithium for acute mania
• Oxcarbazepine in the treatment of acute affective episodes in bipolar disorder: efficacy and acceptability
• Ziprasidone alone or in combination for acute mania